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1临床资料118例患者均经过X线片、CT、MRI及ECT骨扫描等检查,确诊疼痛由溶骨性骨转移引起;所有病例为未用或已停用化疗或放疗4周以上或内分泌治疗和(或)化疗无效者。病例排除标准:①减轻骨转移性疼痛已作放疗者;②对双膦酸盐类药物有过敏史者;③心肝肾功能明显受损
1 clinical data of 118 patients were examined by X-ray, CT, MRI and ECT bone scan, the diagnosis of pain caused by osteolytic bone metastases; all cases of unused or have been discontinued of chemotherapy or radiotherapy for more than 4 weeks or endocrine therapy And / or ineffective chemotherapy. Case exclusion criteria: ① relieve bone metastases pain has been radiotherapy; ② have a history of allergy to bisphosphonates; ③ heart and liver and kidney function was significantly impaired