为确定30岁以上颅内动脉瘤(IA)病人的一级亲属中LA的发生率以及多囊肾病(PCKD)与家族性LA的关系,作者选择1150例IA病人中影响2个以上成员的91个家庭,应用MRA、数字减影血管造影(DSA)对91个家庭中的全部成员普查,同时通过超声检查了PCKD发生情况。 结果 存活的837例一级无症状IA病人中有698例年龄在30岁以上,家族性颅内动脉瘤(FIA)患者的亲属中未发现1例PCKD。完成MRA普查的438例中,女233例,男205例,平均年龄分别为49.3岁和 To determine the incidence of LA in first-degree relatives of patients with intracranial aneurysms (IA) over the age of 30 and the relationship between polycystic kidney disease (PCKD) and familial LA, we selected 91 of 1150 IA patients with more than two members A total of 91 families were surveyed by MRA and DSA. The incidence of PCKD was examined by ultrasonography. Results Of the 837 surviving asymptomatic IA patients, 698 were over 30 years of age and none of the relatives of patients with familial intracranial aneurysm (FIA) had PCKD. Of the 438 MRA censuses performed, 233 were women and 205 were males, with an average age of 49.3 years and