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不宁腿综合征(RLS),又称Willis-Ekbom病,是一种感觉运动障碍性疾病,依据病因可分为特发性和继发性RLS。终末期肾病、规律血液透析(HD)患者中RLS发生率较高,且症状多较特发性RLS重,治疗反应差,常导致透析患者失眠、抑郁、提前终止透析和增加心血管事件风险等,严重影响了这类患者的生活质量和预后。该文就HD患者中RLS可能的发病机制、诊断及鉴别诊断、现有的临床研究和治疗方
Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a sensorimotor dyskinetic disorder that can be divided into idiopathic and secondary RLS based on the cause. End-stage renal disease, regular hemodialysis (HD) patients with a higher incidence of RLS, and symptoms more than idiopathic RLS, poor response to treatment, often leading to dialysis patients with insomnia, depression, early termination of dialysis and increased risk of cardiovascular events , Seriously affecting the quality of life of these patients and prognosis. In this paper, the possible pathogenesis, diagnosis and differential diagnosis of RLS in HD patients, existing clinical research and treatment