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本文应用先进的聚合酶链反应(PCR)技术,检测了27例原发性肝癌(HCC)患者肝癌及癌旁双份组织中的乙肝病毒DNA(HBV DNA),并探讨了与血清学标记物(HBV-M)之间的关系.检测结果表明:癌组织中HBV DNA检出率较癌旁组织中检出率低,且差异有统计学意义(P<0.05).HBsAg阳性合并HBeAg阳性者检出HBV DNA最高,癌旁组织中慢活肝中HBVDNA检出率最高.
In this paper, advanced polymerase chain reaction (PCR) technology was used to detect hepatitis B virus DNA (HBV DNA) in 27 cases of primary liver cancer (HCC) patients with hepatocellular carcinoma and adjacent tissues and to explore serological markers. The relationship between (HBV-M) and test results showed that the detection rate of HBV DNA in cancer tissue was lower than that in adjacent tissues (P<0.05). HBsAg positive patients with positive HBeAg were detected. The highest HBV DNA was detected, and the detection rate of HBV DNA in the non-cancerous liver tissues was the highest.