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目的:探讨超敏C反应蛋白(hs-CRP)在老年脑梗死患者检测中的临床价值。方法:选择佛山市顺德区伍仲珮纪念医院2014年1月至2016年9月老年脑梗死患者100例,根据神经功能缺损评分进行分组,包括轻度、中度、重度3组。另外选择本院同期健康体检者100例作为对照组,使用PA-900特定蛋白分析仪检测hs-CRP,观察和比较老年脑梗死患者和健康体检者的血清hs-CRP。结果:与健康体检者对比,轻度、中度、重度老年脑梗死患者的血清hs-CRP明显更高,与轻度对比,中度、重度患者的血清hs-CRP明显更高,与中度对比,重度患者的血清hs-CRP明显更高,差异具有统计学意义(P<0.05)。结论:血清hs-CRP和老年脑梗死患者动脉粥样硬化具有密切的关系,通过检测血清hs-CRP能够对老年脑梗死患者的病情进行可靠的判断,从而为临床新的治疗方法提供可靠的实验依据,对脑梗死的临床诊断、病情判断、临床预防均具有重要的指导意义。
Objective: To investigate the clinical value of high sensitivity C-reactive protein (hs-CRP) in the detection of senile cerebral infarction. Methods: A total of 100 elderly patients with cerebral infarction from January 2014 to September 2016 in Wuzhong Memorial Hospital of Shunde District of Foshan City were enrolled and divided into three groups according to the neurological deficit score: mild, moderate and severe. In addition, 100 healthy subjects in our hospital were selected as the control group, hs-CRP was detected by PA-900 specific protein analyzer, and the serum hs-CRP in elderly patients with cerebral infarction and healthy subjects was observed and compared. Results: Compared with healthy subjects, serum hs-CRP levels were significantly higher in patients with mild, moderate and severe cerebral infarction. Serum hs-CRP levels were significantly higher in patients with moderate and severe degree than in mild controls, In contrast, severe patients with serum hs-CRP was significantly higher, the difference was statistically significant (P <0.05). Conclusion: There is a close relationship between serum hs-CRP and atherosclerosis in elderly patients with cerebral infarction. The detection of serum hs-CRP can provide a reliable assessment of the condition of elderly patients with cerebral infarction and provide a reliable experimental method for new clinical treatment Based on the clinical diagnosis of cerebral infarction, disease judgment, clinical prevention has an important guiding significance.