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肝转移是内脏和腹膜后肉瘤复发的常见类型;为评价其发病率及生存率与肿瘤分级、分型、原发病灶和治疗方法的关系,作者对981例软组织肉瘤患者中发生肝转移的65例临床资料进行回顾性分析.981例软组织肉瘤的成年患者中65例(7%)合并肝转移.58例(89%)高分化、7例(11%)低分化.55例(85%)为平滑肌肉瘤.65例肝转移病例中,61例(94%)原发病灶在腹内,其中35例在内脏,24例位于腹膜后;原发于四肢或躯干的仅3例.各部位的肝转移发生率分别为:内脏62%,腹膜后16%,四肢躯干0.5%.981例软组织肉瘤患者中,324例发生远隔转移.其中212例肺转移,65例肝转移,26%为其它部位转移.原发于肢端的肉瘤转移至肺、肝比例是75:1;原发于腹膜后的肉瘤转移于肺肝比为1:1.5;内脏肉瘤为1:10.肝累及范围的确定主要依靠剖腹探查或CT.7例为单发转移灶,10例转移灶为多发、局限一叶,48例为多发、两叶均有累及.血管造影显示病灶呈多血管性.两例出现转移性平滑肌肉瘤自发破裂.
Liver metastasis is a common type of recurrence of visceral and retroperitoneal sarcoma; to evaluate the relationship between its incidence and survival rate and tumor grade, type, primary lesions, and treatment methods, the authors examined liver metastases in 981 soft tissue sarcomas. Retrospective analysis of clinical data. Of the 981 adult patients with soft tissue sarcoma, 65 (7%) had liver metastases. 58 (89%) were well-differentiated and 7 (11%) were poorly differentiated. 55 (85%) For leiomyosarcoma, among 65 cases of liver metastases, 61 cases (94%) had primary lesions in the abdomen, of which 35 were in the viscera and 24 were in the retroperitoneum; only 3 were found in the extremities or the trunk. The incidence of hepatic metastasis was 62% of viscera, 16% of retroperitoneum, and 0.5% of the .981 soft tissue sarcomas of the extremities. 324 patients had distant metastases. 212 of them had lung metastases, 65 had liver metastases, and 26% had other diseases. Partial metastasis. The proportion of primary sarcoma metastasized to lungs and liver was 75:1; primary sarcomas after retroperitoneal metastasis were 1:1.5 in lung and liver; visceral sarcoma was 1:10. The extent of liver involvement was mainly determined by The laparotomy or CT.7 cases were solitary metastases, 10 metastatic lesions were multiple, confined to one leaf, 48 cases were multiple, and both leaves were involved. Display angiography showed multiple vascular lesions Two patients had spontaneous rupture of metastatic leiomyosarcoma.