美国目前有超过2万例等待肾移植的HLA致敏患者,这些患者等待移植时间较长,接受移植率较低,病死率增加。针对这种情况,美国研究者对部分致敏患者采用清除供者特异性抗HLA抗体后实施活体肾移植的方案,并比较了该方案的患者存活率是否优于致敏患者继续等待HLA相合肾移植的存活率。 There are currently more than 20,000 HLA-allergenic patients waiting for kidney transplants in the United States. These patients wait longer for transplantation, have lower rates of transplant, and have an increased case fatality rate. In response to this situation, the researchers in the United States used the method of removing donor-specific anti-HLA antibodies to live donor kidney transplantation in some patients who were sensitized and compared whether the survival rate of the patients with this protocol is better than that of patients with allergy and continue to wait for HLA-matched kidney Transplant survival rate.