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血流储备分数是指在存在狭窄病变的情况下,该冠状动脉所提供给心肌区域能获得的最大血流量与同一区域在正常情况下所能获得的最大血流量之比。血流储备分数直接评价受病变影响的血管供血生理功能,它所提供的信息与心肌灌注研究所得相似,但它较后者更为明确且有一个更好的空间分辨率。该指标可广泛应用于冠状动脉各种病变的介入指导,尤其适用于复杂病变如分叉病变和多支弥漫病变,多项研究提示基于血流储备分数的介入治疗具有更好的临床结果。此外,血流储备分数尚可对介入手术的效果及预后进行预测。
Fractional flow reserve is the ratio of the maximum amount of blood flow available to the myocardium from the coronary artery in the presence of stenosis to the maximum amount of blood flow normally available in the same area. The FACS score directly evaluates the physiological function of the blood vessels affected by the lesion, and it provides similar information to the myocardial perfusion study, but it is more specific and has a better spatial resolution than the latter. The index can be widely used in the interventional guidance of various coronary lesions, especially for complex lesions such as bifurcation and multiple diffuse lesions, a number of studies suggest that interventional treatment based on fractional flow reserve has better clinical outcomes. In addition, fractional flow reserve can predict the effect and prognosis of interventional surgery.