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Direct ZnO x-ray detectors with tunable sensitivity are realized by delicately controlling the oxygen flux during the sputtering deposition process.The photocurrents induced by x-rays from a 40kV x-ray tube with a Cu anode increase apparently as the oxygen flux decreases,which is attributed to the introduction of V0 detects.By introducing V0 defects,the annihilation rate of the photo-generated electron-hole pairs will be greatly slowed down,leading to a remarkable photoconductive gain.This finding informs a novel way to design the x-ray detectors based on abundant oxide materials.