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为了防止非造血系统恶性肿瘤病人遭受到威胁生命的细菌感染的危险,一般认为周围血内2,000/立方毫米中性粒细胞是停止化疗的最低的、可接受的极限。然而,一些学者和作者观察到慢性良性中性粒细胞减少的病人,周围血内中性粒细胞虽极度减少(经常低于1,000/立方毫米)其并发这种感染是罕见的。因为成熟的多形核白细胞(PMNs)是有充足的储备,并且当细菌侵入时,作为一种非特异性炎症性刺激的反应而可以从骨髓输送到周围循环移行于组织中,显
To prevent the risk of life-threatening bacterial infections in patients with non-hematological malignancies, it is generally thought that the 2,000 / mm3 neutrophil in the peripheral blood is the lowest and acceptable limit to stopping chemotherapy. However, some scholars and authors observed that in patients with chronic benign neutropenia, peripheral blood neutrophils are extremely rare (often less than 1,000 per cubic millimeter) and concomitant with this infection is rare. Because mature polymorphonuclear leukocytes (PMNs) are well-stocked, and when bacteria invade, they can be transported from the bone marrow to the surroundings as a nonspecific inflammatory stimulus and circulate through the tissues