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目的:通过对本社区2型糖尿病患者糖尿病肾病患病率及危险因素的分析,从而为社区糖尿病和糖尿病肾病管理提供了依据。方法:将176例2型糖尿病患者分为无糖尿病肾病(UAER<20?g/min)组,早期糖尿病肾病(20?g/min200?g/min)3组,统计分析危险因素:病程、腰围和腰臀比、血压、血糖及糖化血红蛋白等与糖尿病肾病的关系。结果:3组糖尿病患者的腰围、餐后2小时血糖、糖化血红蛋白、尿素氮和血肌酐相比,差异有统计学意义(P<0.05);而3组病程差异无统计学意义(P>0.05)。多元逐步回归分析显示糖尿病肾病与糖化血红蛋白、腰围和尿素氮独立相关。结论:糖尿病肾病与糖化血红蛋白和中心性肥胖密切相关,社区管理糖尿病应重视糖化血红蛋白的检测和中心性肥胖的干预。
OBJECTIVE: To provide a basis for community diabetes and diabetic nephropathy management by analyzing the prevalence and risk factors of diabetic nephropathy in type 2 diabetic patients in this community. Methods: One hundred and seventy-six patients with type 2 diabetes were divided into diabetic nephropathy (UAER <20? G / min), early diabetic nephropathy (20? G / min) and UAER > 200? G / min) 3 groups, statistical analysis of risk factors: duration, waist circumference and waist-hip ratio, blood pressure, blood glucose and glycosylated hemoglobin and diabetic nephropathy. Results: There were significant differences in waist circumference, blood glucose, HbA1c, urea nitrogen and serum creatinine between the two groups (P <0.05), but there was no significant difference in the duration of the three groups (P> 0.05 ). Multiple stepwise regression analysis showed that diabetic nephropathy was independently associated with glycosylated hemoglobin, waist circumference, and urea nitrogen. Conclusion: Diabetic nephropathy is closely related to HbA1c and central obesity. Community-based management of diabetes mellitus should pay attention to the detection of HbA1c and the intervention of central obesity.