论文部分内容阅读
药物性肾损害大多表现为急性肾功能不全,急性肾功能不全病例中约有10％是药物性的。当然,也有由于使用某些药物而导致慢性肾损害和特异性肾小管损害。在此,着重讨论药物性急性肾功能不全。肾小球球体毛细血管内压与Bowman腔内压之差为27mmHg,并且肾小球球体毛细血管内皮的面积脉器重量比也比其它脏器的毛细血管内皮面积重量比显著大。同时由于肾小管对肾小球中滤过的药物的再吸
Most of the drug-induced renal damage manifested as acute renal insufficiency, about 10% of acute renal insufficiency cases are drug-based. Of course, due to the use of certain drugs, chronic kidney damage and tubule damage are also caused. Here, focusing on drug-induced acute renal insufficiency. The difference between glomerular capillary pressure and Bowman’s intracavity pressure was 27 mmHg, and the ratio of area veins of the glomerular capillary capillaries was also significantly larger than the capillary endothelial area weights of other organs. At the same time due to renal tubular filtration of drugs in the glomerular reabsorption