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Aesgen公司的左旋谷酰胺(L-glutamine,Safofis)嗽口液可减轻乳腺癌妇女化疗引起的口腔炎,其Ⅲ期临床结果在美国临床肿瘤学会(ASCO)上发表。试验对象是326例在筛选期出现2-4级(即WHO标准的中-重度)口腔炎的蒽环类抗生素化疗乳腺癌妇女。用Saforis或安慰剂治疗两个疗程,两者相比,Safofis使口腔炎
Aesgen’s L-glutamine (Safofis) rinse relieves chemotherapy-induced stomatitis in women with breast cancer and its Phase III clinical results are published at the American Society of Clinical Oncology (ASCO). A total of 326 women with anthracycline chemotherapy breast cancer who had grade 2-4 (moderate to severe WHO) stomatitis at screening stage were included in the study. Compared to two courses of treatment with Saforis or placebo, Safofis makes stomatitis