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目的探讨糖皮质激素治疗儿童眼肌型重症肌无力的疗效。方法 46例儿童眼肌型重症肌无力患者分为甲基强的松龙冲击治疗组34例(A组)、强的松口服治疗组12例(B组);A组首先给予大剂量甲基强的松龙冲击治疗,冲击结束后继续强的松口服;B组开始即强的松口服治疗。结果 A组痊愈28例,显效6例,平均起效时间为3 d,平均最佳疗效时间为9 d;B组痊愈12例,平均起效时间为8 d,平均最佳疗效时间为20 d。结论甲基强的松龙冲击治疗或强的松口服治疗均能使儿童眼肌型重症肌无力痊愈,甲基强的松龙冲击治疗具有起效快、达到最佳疗效时间短、患儿和家长依从性高等优点。
Objective To investigate the efficacy of glucocorticoid in the treatment of ocular myasthenia gravis in children. Methods 46 cases of children with ocular myasthenia gravis patients were divided into 34 cases of methylprednisolone treatment group (group A), prednisone oral treatment group of 12 cases (group B); Group A was first given high-dose methyl Prednisolone impact treatment, after the end of the strong prednisone oral; Group B began prednisone oral treatment. Results A group of 28 patients recovered, markedly effective in 6 cases, the average onset time of 3 d, the average effective time of 9 days; B group cured 12 cases, the average onset time was 8 d, the average best response time of 20 d . Conclusion Methylprednisolone therapy or prednisone oral treatment can make children with myasthenia gravis myasthenia gravis, methylprednisolone impact treatment with fast onset, to achieve the best effect of time is short, children and Advantages of parental compliance.