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目的:分析绝经期综合征合并子宫肌瘤使用克龄蒙治疗后临床疗效与安全性。方法:选取2015年1月至2016年3月在三水区妇幼保健院就诊的41例停经半年以上绝经期综合征合并子宫肌瘤患者(肌瘤单个或者多发性子宫肌瘤,肌瘤直径1.5~3.2 cm),用克龄蒙治疗。比较患者在治疗前后临床症状、子宫肌瘤大小、子宫内膜厚度及雌激素和卵泡刺激素(FSH)的变化。结果:治疗3个月后绝经症状均显著改善,血FSH明显下降,血雌激素明显升高,子宫内膜厚度增厚,与治疗前比较差异具有统计学意义(P<0.05),而子宫肌瘤大小无明显改变,差异无统计学意义(P>0.05)。结论:绝经综合征合并子宫肌瘤经克龄蒙治疗12个月观察,临床疗效显著,对子宫肌瘤大小无明显影响。
Objective: To analyze the clinical efficacy and safety of gram-menopause treatment in menopausal syndrome with uterine fibroids. Methods: From January 2015 to March 2016, 41 cases of menopausal syndrome with menopause syndrome with uterine fibroids (fibroids single or multiple uterine fibroids, fibroid diameter 1.5 ~ 3.2 cm), with gram-age treatment. Before and after treatment in patients with clinical symptoms, uterine fibroids size, endometrial thickness and estrogen and follicle stimulating hormone (FSH) changes. Results: After 3 months of treatment, the symptoms of menopause were significantly improved, the blood FSH was significantly decreased, the blood estrogen was significantly increased, the thickness of endometrium was thicker, which was significantly different from that before treatment (P <0.05) There was no significant difference in tumor size (P> 0.05). Conclusion: The menopause syndrome with uterine fibroids treated by gram-age treatment for 12 months, the clinical efficacy was significant, no significant effect on the size of uterine fibroids.