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目的：探讨良性前列腺疾病患者血清前列腺特异性抗原（ＰＳＡ）与年龄的关系。方法：采用酶联免疫法对２４２例４０～７９岁的良性前列腺疾病患者进行ＰＳＡ测定。结果：不同年龄组其血清ＰＳＡ水平不同，各组上限值为：４０～４９岁组２．５０μｇ／Ｌ，５０～５９岁组３．４９μｇ／Ｌ，６０～６９岁组４．５７μｇ／Ｌ，７０～７９岁组５．５５μｇ／Ｌ。６０～６９岁组、７０～７９岁组较４０～４９岁组、５０～５９岁组患者血清ＰＳＡ测定值显著增高（Ｐ＜０．０５或＜０．０１）。结论：良性前列腺疾病患者其血清ＰＳＡ值有随年龄增加而升高的趋势，在应用ＰＳＡ分析前列腺疾病时，考虑ＰＳＡ与年龄的关系，将有助于提高前列腺疾病的诊断正确率。
Objective: To investigate the relationship between serum prostate specific antigen (PSA) and age in patients with benign prostatic diseases. Methods: 242 cases of benign prostatic diseases aged 40-79 years were measured by enzyme-linked immunosorbent assay. Results: The serum PSA levels in different age groups were different. The upper limit of each group was 2.50μg / L in 40-49 years old group, 3.49μg / L in 50-59 years old group and 4.57μg / L in 60-69 years old group , 70 ~ 79 years old group 5.55μg / L. Serum PSA was significantly higher in patients aged 60-69, 70-79, 40-49, and 50-59 years (P <0.05 or <0.01). Conclusions: The serum PSA level of benign prostatic diseases tends to increase with age. When PSA is used to analyze prostatic diseases, considering the relationship between PSA and age will help to improve the diagnostic accuracy of prostatic diseases.