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本院从1992年7月至1994年12月应用小剂量镇静剂及综合方法治疗中、重型新生儿破伤风25例,其中死亡11例,治愈14例,治愈率56.0％。 临床资料 本组重型21例,中型4例;其中合并肺部感染10例,脓疱疮和消化道出血各2例,硬肿症和佝偻病各1例。死亡病因为,抽搐窒息和呼吸衰竭各5例(占90％),死于并发症1例。全部病例入院后即应用安定、氯丙嗪各5～10mg/d,分次小壶滴入,大部分患儿合并使用鲁米那40～50mg/d,部分患儿加用甘露醇和硫喷妥钠。
The hospital from July 1992 to December 1994 application of low-dose sedative and comprehensive treatment of 25 cases of neonatal tetanus, of which 11 died, 14 cases were cured, the cure rate was 56.0%. Clinical data The group of 21 cases of heavy, 4 cases of medium; which combined pulmonary infection in 10 cases, impetigo and gastrointestinal bleeding in 2 cases, scleredema and rickets in 1 case. The cause of death was convulsive asphyxia and respiratory failure in 5 cases (90%) and 1 case of complications. All patients admitted to the hospital after the use of diazepam, chlorpromazine of 5 ~ 10mg / d, dropping small drops, most of the children combined with luminal 40 ~ 50mg / d, some children plus mannitol and thiopental sodium.