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目的:探讨多器官功能障碍综合征(MODS)并发急性肾损伤(AKI)的相关因素。方法:重症监护病房收治的MODS患者41例,根据是否发生AKI分为AKI组(n=16)及非AKI组(n=25),比较两组患者年龄、性别、基线血肌酐及死亡率等临床资料。结果:AKI组死亡率(50%)明显高于非AKI组(20%),差异有统计学意义(P<0.05);AKI组患者较非AKI组患者年龄大、基线血肌酐水平高、消化道出血及脓毒症发生率高、机械通气时间长,差异有统计学意义(P<0.05)。结论:AKI可明显增加MODS患者的死亡率,其发生与高龄、基线血肌酐高、消化道出血、机械通气及脓毒症有关。
Objective: To investigate the related factors of multiple organ dysfunction syndrome (MODS) complicated with acute kidney injury (AKI). Methods: Forty-one patients with MODS admitted to intensive care unit were divided into AKI group (n = 16) and non-AKI group (n = 25) according to whether AKI occurred, age, sex, baseline serum creatinine and mortality clinical information. Results: The mortality of AKI group (50%) was significantly higher than that of non-AKI group (20%) (P <0.05). AKI group had higher age, baseline serum creatinine level, digestion The incidence of hemorrhage and sepsis was high, the duration of mechanical ventilation was longer, the difference was statistically significant (P <0.05). Conclusion: AKI can significantly increase the mortality of MODS patients. The incidence of AKI is related to the elderly, baseline serum creatinine, gastrointestinal bleeding, mechanical ventilation and sepsis.