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采用微量细胞病变抑制法在Wish细胞上研究了IFN－α2a抗柯萨奇病毒的作用。结果表明：万复洛和罗扰素在Wish细胞上500IU／ml可以抗3lo4，50IU／ml可以抗2log4，5IU／ml可以抗1log4柯萨奇病毒的效应。
The effect of IFN-α2a against Coxsackie virus was studied on Wish cells using the method of micro-cytopathic effect. The results showed that Wanlova and Lo-interferon can effectively resist 1log4 coxsackievirus infection at 500IU / ml on Wish cells and anti-3lo4 at 50IU / ml and anti-2log4,5IU / ml respectively.