论文部分内容阅读
目的 探讨尿核基质蛋白 2 2 (NMP 2 2 )检测和尿脱落细胞学检查在膀胱移行细胞癌诊断中的价值。 方法 对 15 5例怀疑膀胱癌者进行尿NMP 2 2与尿细胞学检查 ,其中 95例经组织学证实为膀胱移行细胞癌。比较两者诊断膀胱癌的敏感性和特异性。 结果 尿NMP 2 2的敏感性为6 5 .3%、特异性为 70 .0 % ;尿细胞学的敏感性为 4 3.2 %、特异性为 83.3%。NMP 2 2在膀胱癌不同分级和分期中的敏感性优于尿细胞学 (P <0 .0 5 )。 结论 尿NMP 2 2检测在早期诊断膀胱癌方面优于尿细胞学检查 ,可以作为膀胱癌的早期检测指标。
Objective To investigate the diagnostic value of urinary nuclear matrix protein 2 2 (NMP 2 2) and urinary exfoliative cytology in the diagnosis of bladder transitional cell carcinoma. Methods Urinary NMP 2 2 and urinary cytology were examined in 15 5 suspected cases of bladder cancer, of which 95 cases were histologically confirmed as bladder transitional cell carcinoma. Compare the sensitivity and specificity of both in diagnosis of bladder cancer. Results The sensitivity of urinary NMP 2 2 was 65.3% and the specificity was 70.0%. The urine cytology sensitivity was 42.2% and the specificity was 83.3%. The sensitivity of NMP 2 2 in different stages and stages of bladder cancer was better than that of urinary cytology (P <0.05). Conclusion Urinary NMP 2 2 is superior to urinary cytology in the early diagnosis of bladder cancer and can be used as an early detection indicator of bladder cancer.