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高脂血症是动脉粥样硬化的一个重要易患因素.特别是纯合子型家族性高胆固醇血症患者在儿童期即可发生重度动脉粥样硬化,很少能活到20岁.最近美国国立卫生研究院脂质研究所发表的资料,其结论为:降低血浆胆固醇浓度可使冠心病的易患性下降.临床医师只有充分了解脂质转运的生理和生化,才能理解高脂血症在动脉粥样硬化中所起的作用.本文概述脂蛋白和载脂蛋白的代谢.
Hyperlipidemia is an important predisposing factor for atherosclerosis, especially in patients with homozygous familial hypercholesterolemia who develop severe atherosclerosis during childhood and seldom survive until the age of 20. Recently, the United States Lipid Institute of National Institutes of Health published data concluded that: lower plasma cholesterol levels can reduce the susceptibility of coronary heart disease clinicians only fully understand the physiological and biochemical lipid transport in order to understand the hyperlipidemia in Atherosclerosis This article outlines the metabolism of lipoproteins and apolipoproteins.