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本工作的目的是研究急性高原低氧对豚鼠听觉传入功能的影响。２０只豚鼠分为４组，分别接受模拟海拔高度为５０００、６０００、７０００和８００ｏｍ的急性低氧暴露，于不同时间测定听觉脑干诱发反应各波的潜伏期、峰间期、振幅和ＩＩＩ波的电反应阈（听阈）。结果如下：当升至预定的海拔高度和在低氧维持阶段，６０００ｍ以上组各波潜伏期延长，其中ＩＩ波变化更明显；回到海平面高度后逐渐恢复，１ｈ内基本可恢复正常；潜伏期变化的程度与海拔高度有关。在低氧阶段各波振幅普遍下降，回到海平面高度后逐渐回升，但恢复至正常所需时间较长。在升至预定的海拔高度和其后低氧维持阶段，各组动物的听阈均上升，脱离低氧后即可迅速恢复，１ｈ内可恢复正常。结果表明，急性高原低氧使听觉脑干传导时间延长，传入神经元兴奋性降低，听敏度下降，因而可以推测它能影响声信号的传入。
The purpose of this study was to investigate the effect of acute plateau hypoxia on auditory afferent function in guinea pigs. Twenty guinea pigs were divided into 4 groups and received acute hypoxic exposure at simulated altitude of 5000, 6000, 7000 and 800om, respectively. The latency, peak period, amplitude and III wave of each wave of auditory brainstem response Electrical reaction threshold (threshold). The results were as follows: When reaching the predetermined altitude and in the stage of hypoxia maintenance, the latency of each wave of above 6 000 m was prolonged, of which the II wave changed more obviously; returned to sea level and recovered gradually within 1 h; The extent and altitude. During the hypoxia phase, the amplitudes of the waves generally decreased and returned gradually to the sea level, but the recovery time to normal was longer. After rising to a predetermined altitude and subsequent hypoxia maintenance phase, the hearing threshold of each group of animals increased rapidly, recovered rapidly after leaving hypoxia, and returned to normal within 1 h. The results showed that acute plateau hypoxia prolonged the conduction time of auditory brainstem, lowered the excitability of afferent neurons and decreased the hearing sensitivity, so it can be speculated that it can affect the afferent signal.