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目的比较甘肃天祝县与兰州市两地区居民幽门螺杆菌感染状况,并考察各种相关因素对其感染率的影响。方法采用血清Helicobacterpylori IgG抗体金标渗滤斑点法和14 C 尿素呼气试验检测1780例2 0岁以上居民的H .pylori感染情况。结果天祝县H .pylori感染率76.8% ,显著高于兰州市的5 8.4% (P <0 .0 1)。汉藏两族及男女两性相比,其感染率均无显著差异(P >0 0 5 )。Hp感染与饮水源显著相关,饮用自来水者感染率显著低于饮用池塘/沟渠/河水和井水者(P <0 .0 1。H .pylori感染与人均年收入、碗筷洗刷情况、便后洗手和上消化道症状相关(P <0 .0 5 )。结论天祝和兰州两地区的H .pylori感染率均较高,且前者显著高于后者。H .pylori感染与饮用水源、生活卫生习惯、经济状况和上消化道症状等流行因素显著相关。
Objective To compare the prevalence of Helicobacter pylori infection between residents in Tianzhu County and Lanzhou City in Gansu province and investigate the influence of various related factors on the infection rate. Methods H. pylori infection in 1780 residents over 20 years of age was detected by the gold standard of serological Helicobacter pylori IgG antibody and 14 C urea breath test. Results The infection rate of H.pylori in Tianzhu County was 76.8%, significantly higher than that in Lanzhou City (8.42%, P <0.01). There was no significant difference in the infection rates between Han and Tibetan families and between men and women (P> 0.05). Hp infection was significantly associated with drinking water sources, and the prevalence of drinking tap water was significantly lower than that of drinking ponds / ditches / river water and well water (P <0.01, H. pylori infection and per capita annual income, washing tableware, then Wash hands and upper gastrointestinal symptoms (P0.05) .Conclusion The infection rates of H.pylori in Tianzhu and Lanzhou were higher than those in the latter, and the former was significantly higher than the latter.H.pylori infection was associated with drinking water sources, Living health habits, economic status and upper gastrointestinal symptoms and other epidemic factors were significantly correlated.