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本文观察了用大剂量维生素B_6治疗的60例巴金森氏综合征患者,其中特发性23例,脑炎后12例,血管性25例.男性36例,女性24例.中年患者22例,老年患者31例,高龄患者7例,大多数患者病程2到10年.作者选择以震颤为主的患者用维生素B_6治疗,26例单用维生素B_6,其余的34例继续并用中枢性抗胆碱药.用大剂量维生素B_6的治疗下,作者发现12例震颤显著减少到完全消失.无论是静止性、姿势性、运动性及头、下颔、舌的震颤都明显减少.情况改善的43例,运动性与姿势性震颤表现为振幅减小,静止性震颤振幅减小不大.如果治疗前震颤是持续的,那么治疗后则为间歇性的;如果震颤是不持续的,那么主动运动后静止性震颤消失的时间也明显延长.
This article observed 60 patients with Parkinson’s disease treated with high-dose vitamin B_6, idiopathic 23 cases, 12 cases of post-encephalitis, vascular 25 cases, 36 males and 24 females in middle-aged patients 22 cases 31 cases of elderly patients, 7 cases of elderly patients, most patients with duration of 2 to 10 years.The author chooses tremor-based patients with vitamin B_6 treatment, 26 cases of single vitamin B_6, and the remaining 34 cases continue to use central anticholinergic. With high-dose vitamin B_6 treatment, the authors found that 12 cases of tremor significantly reduced to completely disappear. Whether static, posture, mobility and head, lower jaw, tongue tremor was significantly reduced in 43 cases of improvement, exercise Sexual and Postural Tremor Shows Decreased Amplitude and Restless Tremor Amplitude Reduced Little If pre-treatment tremor is persistent, then the treatment is intermittent; if the tremor is not sustained, the post-active rest Tremor disappeared significantly longer time.