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谷氨酸能刺激糖代谢和氧化还原过程,维持机体在氟化钠中毒时氨的正常代谢,加速氟从尿中的排泄。实验采用HF、MoF_6、WF_6吸入中毒。急性实验用小鼠在氟离子浓度为110±15mg/m~3中吸入2小时,亚急性实验在30～40mg/m~3浓度中10天时间内每天吸入4小时,慢性实验用大鼠在1.5±0.54mg/m~3浓度中4个月时间内每天吸入5小时。实验动物分吸入中毒谷氨酸治疗组、吸入中毒生理盐水组和对照组。
Glutamate stimulates glucose metabolism and redox processes, maintaining the body’s normal metabolism of ammonia during sodium fluoride poisoning and accelerating the excretion of fluoride from the urine. Experimental use HF, MoF_6, WF_6 inhalation poisoning. Acute experimental mice were inhaled for 2 hours at a fluoride ion concentration of 110 ± 15 mg / m ~ 3. Subacute experiments were inhaled for 4 hours at a concentration of 30-40 mg / m ~ 3 for 10 days. Chronic experimental rats 1.5 ± 0.54mg / m ~ 3 concentration in 4 months time inhalation 5 hours a day. Into the experimental animals were poisoned glutamate treatment group, inhalation poisoning saline group and control group.