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目的探讨米非司酮配伍米索前列醇终止早期妊娠致阴道流血过多的相关因素及防治措施。方法分析2000年7月至2006年9月发生的83例药物流产后流血量＞100 ml患者的出血原因。结果药物流产阴道出血过多的原因与孕龄、胚胎组织排出时间、追加米索前列醇用量及组织残留情况存在密切关系,与孕妇年龄无关。结论药物流产后出血时间长及阴道出血过多引起的危险是药物流产的最大缺点。预防药物流产后多量阴道流血的措施是严格掌握门诊药物流产指征,适时刮宫,预防感染,探讨改进药物流产方案,延长米非司酮的应用时间等。
Objective To investigate the related factors and preventive measures of mifepristone with misoprostol in ending vaginal bleeding caused by early pregnancy. Methods The causes of bleeding in 83 patients with bleeding> 100 ml after medical abortion were analyzed from July 2000 to September 2006. Results The causes of excessive vaginal bleeding in medical abortion were closely related to the gestational age, the time of embryo tissue excretion, the amount of misoprostol added and the residual tissue, which had nothing to do with the age of pregnant women. Conclusion The long-term bleeding after medical abortion and excessive bleeding caused by vaginal bleeding is the biggest drawback of medical abortion. Prevention of medical abortion after a large number of vaginal bleeding measures are strictly outpatient medical abortion indications, timely curettage, prevention of infection, to explore the improvement of medical abortion program to extend the application of mifepristone time.