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目的探讨幽门螺旋杆菌阳性消化性溃疡采用雷贝拉唑三联法治疗的效果。方法随机选自我院在2015年3月~2016年1月收治的幽门螺旋杆菌阳性消化性溃疡患者70例，采取随机、对照、平均分成两组的方式，分别命名为观察组及对照组。对观察组35例患者采用雷贝拉唑三联法治疗，对对照组35例患者采用奥美拉唑三联法治疗。结果观察组患者临床治疗的有效率、前2个疗程症状改善率及治疗期间的生活质量高于对照组患者，不良反应发生率低于对照组患者，住院时间短于对照组患者。结论雷贝拉唑三联法治疗幽门螺旋杆菌阳性消化性溃疡疗效显著，安全性高，可进行临床广泛性推广。“,”Objective The Helicobacter pylori-positive peptic ulcer effect of using triple therapy method. Methods Random selected in our hospital from March 2015 to January 2016 were treated 70 cases of H. pylori-positive peptic ulcer patients, randomized, controlled, were divided into two groups of ways, were named as the observation group and the control group. Observation group of 35 patients were treated with triple therapy method for the control group of 35 patients were treated with Triple Therapy. Results The patients with clinical efficiency, quality of life was higher in patients with symptom improvement rate for each treatment and during treatment, incidence of adverse reactions than the control group patients. Conclusion Treatment of triple H. pylori-positive peptic ulcer a significant effect, safe, available for extensive clinical promotion.