老年男性Ⅱ型糖尿病患者血清性激素变化及与冠心病的关系

来源 :中国老年学杂志 | 被引量 : 0次 | 上传用户:rlh1911
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对≥60岁的男性Ⅱ型糖尿病(Ⅱ-DM)患者及合并冠心病患者各50例进行研究,测定其血清T、E2、血糖(GLU)、TC、TG水平。结果:男性Ⅱ-DM及合并冠心病患者血清T低于健康对照组(P<0.05和P<0.01),血清E2也有下降趋势(P>0.05),E2/T比值则高于对照组(P>0.05);相关分析显示T与GLU、TC、TG均呈负相关(P<0.01),而E2则似乎与GLU、TC、TG无明显相关性,GLU与TC、TG呈正相关(P<0.01)。结论:Ⅱ-DM及冠心病患者均存在性激素改变,并与血糖、血酯一起构成影响糖尿病、冠心病的不利因素。 Fifty cases of type Ⅱ diabetes mellitus (DM) and coronary heart disease (CHD) of ≥60 years old were studied. Serum levels of T, E2, GLU, TC and TG were measured. Results: Serum T was lower in male Ⅱ-DM patients with coronary heart disease than in healthy controls (P <0.05 and P <0.01), serum E2 was also decreased (P> 0.05), and E2 / T ratio (P <0.05). Correlation analysis showed that there was a negative correlation between T and GLU, TC, TG (P <0.01), while E2 did not seem to have a significant correlation with GLU, TC, TG, GLU And TC, TG was positively correlated (P <0.01). Conclusion: Both sex hormones are present in patients with Ⅱ-DM and coronary heart disease, and together with blood glucose and blood lipid, they constitute the unfavorable factors that affect diabetes and coronary heart disease.
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