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目的探讨大型妇产医院羊水过少患者的诊疗特征,并通过对其治疗方法的比较选择最有效的治疗方法。方法回顾分析大型妇产医院106例羊水过少患者的诊疗资料,对临床干预措施进行统计。结果 (1)大型妇产医院中羊水过少者占同期住院分娩的0.82%(106/12885)。(2)羊水过少患者进行母体静脉水化疗法48例,占45.3%(48/106),行羊膜腔灌注治疗2例,占1.9%(2/106)。(3)羊水过少者中妊娠结局为胎儿畸形及流产者10例,占9.4%(10/106),羊水过少而未治疗者46例,占43.4%(46/106),且转归较差。(4)对羊水过少者进行药物治疗有效者其自然分娩比例为66.7%,明显高于治疗无效者4.2%,且差异具有统计学意义(χ2=20.49,P<0.001)。(5)双因素方差分析表明单用丹参或川芎嗪治疗的疗效劣于两种药物合用(P<0.05)。结论大型妇产医院羊水过少者未治疗者仍占较大比例,通过治疗可以降低剖宫产率,联合丹参和川芎嗪的母体静脉水化疗法有显著疗效。
Objective To investigate the diagnosis and treatment of patients with oligohydramnios in large maternity hospital and to choose the most effective treatment by comparing their treatment methods. Methods The clinical data of 106 cases of oligohydramnios in large maternity hospital were retrospectively analyzed. The clinical interventions were statistically analyzed. Results (1) In the large maternity hospital, oligohydramnios accounted for 0.82% (106/12885) of hospital delivery in the same period. (2) 48 cases (45.3%) were treated by maternal venous hydropathy with oligohydramnios, and 2 cases received amniotic perfusion (1.9%, 2/106). (3) In the oligohydramnios, the pregnancy outcome was fetus deformity and abortion in 10 cases (9.4%), oligohydramnios without treatment in 46 cases (43.4%, 46/106) Poor. (4) The rate of spontaneous delivery of patients with oligohydramnios was 66.7%, significantly higher than 4.2% of those with ineffective treatment, the difference was statistically significant (χ2 = 20.49, P <0.001). (5) Two-way ANOVA showed that the curative effect of Salvia miltiorrhiza or ligustrazine alone was inferior to that of the two drugs (P <0.05). Conclusion Large oligohydramnios in large maternity hospital who still have a large proportion of untreated patients can reduce the rate of cesarean section through treatment, combined with Salvia miltiorrhiza and ligustrazine in maternal venous hydration has a significant effect.