氟的神经毒性的防治研究已引起关注。鉴于氟中毒微量元素失衡可能同自由基代谢具内在联系 ,其中微量元素碘、硒和氟中毒的关系较为密切。我们前期研究已表明 ,一定浓度的硒 (1 5mg/L)对氟致小鼠分辨学习能力的损伤有明显的拮抗作用 ;近期的研究已经提示 ,碘与氟对有关靶器官的 Fluorine neurotoxicity prevention and control has attracted much attention. In view of the imbalance of trace elements in fluoride poisoning may be inherently linked with free radical metabolism, which trace elements iodine, selenium and fluoride poisoning are more closely related. Our previous studies have shown that a certain concentration of selenium (15mg / L) has a significant antagonistic effect on the impairment of learning ability induced by fluorine in mice; recent studies have shown that iodine and fluoride on target organs