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目的了解晚期妊娠合并HIV感染,在给予抗病毒治疗的基础上两种分娩方式发生母婴垂直传播的几率。方法 2005年1月至2010年12月就诊的26例HIV感染孕妇,阴道分娩成功11例为研究组,剖宫产病例15例(其中择期手术9例,产科合并症剖6例)为对照组,对其进行回顾性分析。结果两组患者经1年随访,新生儿人工喂养在0、3、6、12个月进行HIV抗体检测,研究组母婴垂直传播发生1例(9.09%),对照组母婴垂直传播发生1例(6.67%),两组差异无统计学意义(P<0.05)。结论 HIV感染孕妇在抗病毒治疗的基础上,阴式分娩与剖宫产分娩母婴垂直传播发生率无明显差异。
Objective To understand the risk of vertical transmission of mother-infant transmission in late pregnancy with HIV infection on the basis of antiviral therapy in both modes of delivery. Methods From January 2005 to December 2010, 26 HIV-infected pregnant women were treated by vaginal delivery. Eleven cases of vaginal delivery were study group. 15 cases of cesarean section (including 9 cases of elective surgery and 6 cases of obstetric complications) were used as control group , A retrospective analysis of its. Results The HIV antibody test was conducted at 0, 3, 6, and 12 months after birth in one group in two groups. One case (9.09%) of the mother-infant vertical transmission in the study group and one case of the vertical transmission in the control group Cases (6.67%), no significant difference between the two groups (P <0.05). Conclusion On the basis of antiviral therapy, there is no significant difference in the incidence of vertical transmission of mother-infant between vaginal delivery and cesarean section in HIV-infected pregnant women.