霍乱弧菌是河口与海洋环境中自然微生物区系的成员。霍乱弧菌在诸如低温、低盐和低营养物浓度的不良环境条件下,可以变成非可培养状态。利用活菌直接镜检技术和免疫萤光抗体染色技术证明,霍乱弧菌是活的非可培养状态。实验还证明霍乱弧菌的越冬是通过活的非可培养状态实现的。 Vibrio cholerae is a member of the natural microflora in estuarine and marine environments. Vibrio cholerae can become non-culturable under adverse environmental conditions such as low temperature, low salt and low nutrient concentrations. Vibrio cholerae is a viable, non-culturable state by direct microscopic examination of live bacteria and immunofluorescent antibody staining. Experiments also show that the overwintering of Vibrio cholerae is achieved through living non-culturable conditions.