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我们对600例停经42天内的早孕妇女分两组分别应用米非司酮联合紫草配伍米索前列醇及米非司酮配伍米索前列醇进行药物流产,结果表明米非司酮联合紫草组的完全流产率(99.00%)明显高于米非司酮组(92.33%)(P<0.01).前者用米非司酮和紫草后孕囊排出时间(54.01±7.55小时)及服用米索前列醇后6小时内的孕囊排出率(82.33%)较后者(56.41±9.93小时、72.67%)明显缩短和升高(P均小于0.05),且出血时间(7.01±3.11天)和出血时间超过10天的发生率(12.46%)亦较后者(8.09±5.63天,24.91%)明显缩短和减少(P值分别小于0.05和0.01).两组流产后月经转复天数无明显差别(P>0.05).由此可见,紫草可提高米非司酮药物流产的成功率、缩短出血时间,因此有必要对其提高药物流产效果的作用进行进一步的探讨.
We 600 cases of early pregnancy within 42 days of menopause women were divided into two groups were treated with mifepristone combined with Lithospermum with misoprostol and mifepristone with misoprostol for medical abortion, the results show that mifepristone combined with Lithospermum The complete abortion rate (99.00%) was significantly higher in the mifepristone group (92.33%) than in the mifepristone group (P <0.01) The gestational sac discharge rate (82.33%) was significantly shorter and higher than that of the latter (56.41 ± 9.93 hours, 72.67%) within 6 hours after surgery (P <0.05) and bleeding time (7.01 ± 3.11 days) and Bleeding time more than 10 days (12.46%) than the latter (8.09 ± 5.63 days, 24.91%) was significantly shorter and less (P values were less than 0.05 and 0.01) .The two groups did not differ significantly after menstruation days recovery (P> 0.05) .Therefore, Lithospermum can improve the success rate of mifepristone abortion and shorten the bleeding time, so it is necessary to further explore its effect of improving the abortion effect.