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目的探讨左乙拉西坦添加治疗儿童部分性癫痫的临床疗效及耐受性。方法观察42例部分性癫痫患儿采用左乙拉西坦添加治疗后疗效,不同发作类型的有效率以及发作频率的改变。结果左乙拉西坦添加治疗,总有效率为69%。简单部分性发作有效率68%,复杂部分性发作有效率73%,部分性发作转为全面性发作有效率67%。添加治疗后患儿月发作频率减少38.1%,治疗前后差异显著(P<0.05)。不良反应轻微。结论左乙拉西坦添加治疗儿童部分性癫痫具有较好的临床疗效及耐受性。
Objective To investigate the clinical efficacy and tolerability of levetiracetam in children with partial epilepsy. Methods 42 children with partial epilepsy were treated with levetiracetam after curative effect, different types of seizure efficiency and seizure frequency changes. Results levetiracetam add treatment, the total effective rate was 69%. 68% of simple partial seizures, 73% of complex partial seizures, and 67% of partial seizures into full-blown seizures. The frequency of monthly seizures decreased 38.1% after treatment, with significant difference before and after treatment (P <0.05). Minor adverse reactions. Conclusion Levetiracetam added in children with partial epilepsy has good clinical efficacy and tolerance.