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同种异体角膜移植无法改善病人视力时,人工角膜的应用是使部分全角膜白斑盲人复明的重要途径之一。1969～1978年,我院共计为82例病人施行人工角膜移植,部分盲人获得有用视力达3年左右,但大部分病例术后视力周期仅为几个月至一年。以往临床实践证实:由于人工角膜镜柱外周与光学窗口处角膜之间存在半开放性缝隙,使周围角膜基质变薄和坏死,房水溢漏和镜后长膜,最终导致人工角膜脱落。为此,我们设想寻找与角膜生理特性接近的物质,它应具
The allograft corneal transplantation can not improve the patient’s visual acuity, the application of artificial cornea is part of the whole corneal leukoplakia blind one of the important ways. From 1969 to 1978, a total of 82 patients underwent artificial corneal transplantation in our hospital. Some blind people acquired useful visual acuity for about 3 years, but in most cases, the visual acuity period is only a few months to a year. Previous clinical practice confirmed that: due to the existence of semi-open gap between the cornea of the cornea and the optical window at the periphery of the cornea, thinning and necrosis of the surrounding corneal matrix, aqueous humor leakage and long after the film, eventually leading to corneal shedding. To this end, we envision looking for a substance that is close to the physiological properties of the cornea and it should have