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目的 评价七氟醚复合利多卡因表面麻醉在小儿唇腭裂手术中应用的临床效果.方法 40 例ASA Ⅰ-Ⅱ级的唇腭裂患儿随机分为2组,每组20 例.A组采用氯胺酮进行麻醉诱导,B组采用七氟烷复合利多卡因.比较两组患者的诱导时间、插管时保留自主呼吸情况、呛咳情况、苏醒时间等.结果 所有患儿均顺利完成诱导和插管过程.与传统氯胺酮诱导麻醉方法比较,诱导时间、苏醒时间缩短,七氟烷复合利多卡因表面麻醉在插管时保留了自主呼吸.结论 在唇腭裂手术麻醉中,七氟烷复合利多卡因表面麻醉为小儿麻醉诱导提供了另外一种方法,不亚于传统的氯胺酮麻醉诱导方法.“,”Objective To evaluate the clinical benefit of sevoflurane combined with lidocaine for topical anesthesia for cleft lip and palate repair in children. Methods 40 ASA Ⅰ-Ⅱ children undergoing elective cleft lip and palate repair were randomly divided into two groups, 20 in each group. Anesthesia induction was performed with ketamine in group A, and sevoflurane combined with lidocaine in group B. The induction time, retention of spontaneous respiration during endotracheal intubation, choking cough and awakening time were compared between the two groups. Results All children finished the process of induction and intubation uneventfully. Compared with the traditional ketamine induced anesthesia, the method of sevoflurane combined with lidocaine retained spontaneous breathing during intubation and the induction time and awakening time were shorter. Conclusion Sevoflurane combined with lidocaine for topical anesthesia provides another method for anesthesia induction in cleft lip and palate repair, which is no less than the traditional ketamine anesthesia induction method.