论文部分内容阅读
从70年代初就有学者对质子泵进行研究,并以质子泵作为开发研究新的抑制胃酸分泌药物的靶目标。1989年第一种质子泵抑制剂奥美拉唑上市。因它比组胺H_2受体拮抗剂更有效地抑制胃酸分泌,而且药理效应持续时间长,对与胃酸相关的疾病的疗效显著,因此,为胃肠道疾病的治疗发挥了重要作用。 泮托拉唑Pantoprazole(潘妥洛克Pantoloc,Pantozol)是继奥美拉唑、兰索拉唑之后上市的第
Since the early 1970s, some scholars have conducted research on proton pumps, and proton pumps have been used as a target for developing new inhibitors of gastric acid secretion. In 1989 the first proton pump inhibitor omeprazole listed. Because it is more effective than histamine H 2 receptor antagonist inhibition of gastric acid secretion, and pharmacological effects for a long time, the effect of gastric acid-related diseases significantly, therefore, for the treatment of gastrointestinal diseases has played an important role. Pantoprazole (Pantoloc, Pantozol) is the second most popular omeprazole and lansoprazole