作者用~3H-TdR掺入抑制试验检测40例健康人(男18例,女22例)外周血NK细胞活性,结果显示:抑制百分率男性为45.6±9.1％,女性为43.2±9.0％,平均为44.3±9.1％,男女之间无显著性差异(P>0.20)。本法操作简便、重复性好,与常用的~(51)Cr释放试验比较,所需标本量少,~3H半衰期较~(51)Cr长,二者结果呈良好的正相关(r=0.873,P<0.01),是一种有应用价值的检测人外周血NK细胞活性的新方法。 The authors used the ~3H-TdR incorporation inhibition test to detect peripheral blood NK cell activity in 40 healthy subjects (18 males and 22 females). The results showed that the percentage of inhibition was 45.6 ± 9.1% for males and 43.2 ± 9.0% for females. There was no significant difference between males and females (44.3±9.1%) (P>0.20). This method is simple and reproducible, and compared with the commonly used ~(51)Cr release test, the amount of specimen required is small, and the half-life of ~3H is longer than that of ~(51)Cr, and the results are positively correlated (r = 0.873). (P<0.01) is a new method for detecting NK cell activity in human peripheral blood.