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本文报告原发性胃腺鳞癌4例,占本所同期胃癌的0.44％。作者讨论了本病的组织学起源,其中以腺癌鳞化发生腺鳞癌的可能性较大。它的起源方式可能与胃纯鳞癌有所不同。肿瘤中的腺癌和鳞癌两种成分可同时或分别转移,故提示它们的生物学行为存有差异。本病预后较差。治疗采用包括根治性手术、化疗等在内的综合治疗,但以根治性手术治疗为主。
This article reports 4 cases of primary gastric adenosquamous carcinoma, accounting for 0.44% of gastric cancer in the same period. The authors discussed the histological origin of the disease, of which the adenocarcinoma was more likely to become adenosquamous carcinoma. Its origin may be different from that of pure squamous cell carcinoma of the stomach. The two components of adenocarcinoma and squamous cell carcinoma can metastasize simultaneously or separately, suggesting that there are differences in their biological behavior. The prognosis of the disease is poor. The treatment includes comprehensive treatment including radical surgery and chemotherapy, but radical surgery is the main treatment.