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1948年塞里氏首先报道胃肠道在应激状态下粘膜发生糜烂、出血和溃疡。其后,应用胃镜作早期检查以来,应激性溃疡的发现率明显增加。应激性溃疡占胃肠溃疡的发病率0～35％,发病率之悬殊,可能是应激病因增加,或是对胃肠道粘膜的应激病变认识不一所致,近年来有关应激性溃疡的病因、发病机理和处理方法均有不少进展,现综述如下。
Serie 1948 first reported gastrointestinal mucosal erosion, bleeding and ulcers in the stress state. Since then, the application of gastroscopy for early detection, the detection rate of stress ulcers increased significantly. Stress ulcer accounts for the incidence of gastrointestinal ulcer 0 to 35%, the incidence of disparity may be due to increased stress causes, or gastrointestinal mucosa of the different understanding of the disease caused by stress in recent years, the stress The causes of ulcer, the pathogenesis and treatment methods have made a lot of progress, are summarized below.