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目的:评价吡柔比星和丝裂霉素膀胱灌注疗法对腺性膀胱炎(CG)患者的临床疗效。方法:选取2013年1月—2015年月间收治的腺性膀胱炎患者65例,将其分为观察组34例和对照组31例;对照组患者在尿道钬激光手术配合下给予丝裂霉素膀胱灌注治疗,观察组虱在对照组基础上加用吡柔比星膀胱灌注治疗;比较两组患者治疗后的总有效率和复发率。结果:观察组患者治疗后的总有效率为88.24%高于对照组为64.52%(P<0.05),复发率低于对照组(P<0.05)。结论:采用膀胱灌注吡柔比星和丝裂霉素治疗腺性膀胱炎患者,经尿道钬激光手术配合下其临床疗效较佳,术后不易复发。
PURPOSE: To evaluate the clinical efficacy of pirarubicin and mitomycin C in bladder glandular cystitis (CG) patients. Methods: Totally 65 patients with glandular cystitis admitted from January 2013 to January 2015 were divided into observation group (34 cases) and control group (31 cases). Patients in control group underwent urethral holmium laser surgery combined with mitomycin C The treatment of bladder irrigation, observation group lice on the basis of the control group with pirarubicin bladder irrigation treatment; comparison of the two groups of patients after treatment, the total effective rate and recurrence rate. Results: The total effective rate of the observation group after treatment was 88.24% higher than that of the control group (64.52%, P <0.05), and the recurrence rate was lower than that of the control group (P <0.05). CONCLUSIONS: Intravesical instillation of pirarubicin and mitomycin for patients with glandular cystitis shows better clinical efficacy with transurethral holmium laser surgery and less recurrence after surgery.