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目的对感染呼吸道合胞病毒产生的Th1、Th2型细胞因子种类及其对Th1/Th2型反应平衡的影响进行综述。方法在查阅国内外文献的基础上,介绍各种细胞因子在呼吸道合胞病毒(RSV)感染中的作用、地位。结果与结论虽然到目前为止各种细胞因子在各实验中得出的结果,甚者是对于RSV感染更倾向于发生Th1型还是Th2型反应仍有争论,但Th1/Th2反应平衡在RSV治疗和开发防治药物方面仍具有重要意义。
Objective To summarize the types of Th1 and Th2 cytokines produced by respiratory syncytial virus and their effects on the Th1 / Th2 response balance. Methods Based on the literature review both at home and abroad, the roles and status of various cytokines in respiratory syncytial virus (RSV) infection were introduced. RESULTS AND CONCLUSION Although the results of the various cytokines so far obtained in each experiment are still debated whether Th1-type or Th2-type reactions are more prevalent in RSV infections, the balance of Th1 / Th2 responses is not significantly different between RSV-treated and Development of drug control is still of great significance.