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Several studies have reported infection as a possible risk factor for cervical artery dissection(CAD).We retrospectively analyzed several inflammatory parameters of CAD patients with the aim of detecting differences between spontaneous(n = 25)and traumatic(n=18)CAD.In this case-control study,we observed significantly higher absolute leucocyte values(10.3 versus 8.1 G/L;p = 0.02)as well as an elevated frequency of leucocytosis(64%versus 28%;p = 0.02)and elevated CRP(60%versus 28%;p = 0.04)in patients without a history of trauma(“spontaneous”CAD)compared with patients with trauma related CAD.As the elevated inflammatory laboratory parameters were not associated with an elevated infection rate,these findings imply a role of an acute inflammation as a pathogenetic factor in spontaneous CAD.The cause and mechanism of the inflammatory process remain unknown.
Several studies have reported infection as a possible risk factor for cervical artery dissection (CAD). We retrospectively analyzed several inflammatory parameters of CAD patients with the aim of detecting differences between spontaneous (n = 25) and traumatic (n = 18) CAD. This case-control study, we observed significantly higher absolute leucocyte values (10.3 versus 8.1 G / L; p = 0.02) as well as an elevated frequency of leucocytosis (64% versus 28% versus 28%; p = 0.04) in patients without a history of trauma (“spontaneous” CAD) compared with patients with trauma related CAD.As the elevated inflammatory laboratory parameters were not associated with an elevated infection rate, these findings imply a role of an acute inflammation as a pathogenetic factor in spontaneous CAD. The cause and mechanism of the inflammatory process remain unknown.