论文部分内容阅读
目的:观察分析慢性心力衰竭(CHF)患者N末端脑钠肽前体(NT-proBNP)、肌钙蛋白(CTnI)、超敏C反应蛋白(hsCRP)的水平变化及其临床意义。方法:选取我院2015年2月-2016年2月收治的80例慢性心力衰竭患者视为观察组,选取同时健康体检者20例作为对照组,对两组患者NT-proBNP、CTnI、hs-CRP进行测定。结果:观察组患者hs-CRP、cTnI、NTproBNP水平较对照组健康人员明显提高(P<0.05);不同心功能分级患者NT-proBNP、cTnI差异显著,随着心功能分级的增高,NT-proBNP、cTnl呈上升趋势(P<0.05),hs-CRP水平比较无统计学意义(P>0.05)。结论:对患者NT-proBNP、CTnI、hs-CRP进行检测,可科学、客观地反映出患者病情,为临床诊断、治疗、预后提供专业参考。
Objective: To observe the changes of N-terminal pro-brain natriuretic peptide (NT-proBNP), troponin (cTnI) and hsCRP in patients with chronic heart failure (CHF) and their clinical significance. Methods: Totally 80 chronic heart failure patients treated in our hospital from February 2015 to February 2016 were selected as the observation group. Twenty healthy subjects at the same time were selected as the control group. NT-proBNP, CTnI, hs- CRP determination. Results: The levels of hs-CRP, cTnI and NTproBNP in the observation group were significantly higher than those in the control group (P <0.05). NT-proBNP and cTnI in the patients with different cardiac function scores were significantly different. , CTnl was increased (P <0.05), hs-CRP levels were not statistically significant (P> 0.05). Conclusion: The detection of NT-proBNP, CTnI and hs-CRP in patients can reflect the patient’s condition scientifically and objectively and provide professional reference for clinical diagnosis, treatment and prognosis.