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The radioprotective effects of 6 Gui-Pi-Wan extracts were investigated by examining cell viability and 30-d survival of mice after total-body 60Co irradiation.Pretreatment with Gui-Pi-Wan precipitate by water extraction and alcohol precipitation(PWA) prior to irradiation resulted in significantly higher cell survival and lower apoptosis rates at 24 h after 5 Gy radiation,and increased 30-d survival in mice after exposure to a potentially lethal dose of 8 Gy.These results collectively indicate that PWA of Gui-Pi-Wan extracts is an effective radioprotective agent.
The radioprotective effects of 6 Gui-Pi-Wan extracts were investigated by examining cell viability and 30-d survival of mice after total-body 60Co irradiation. Pleating with Gui-Pi-Wan precipitate by water extraction and alcohol precipitation (PWA) prior to irradiation resulted in significantly higher cell survival and lower apoptosis rates at 24 h after 5 Gy radiation, and increased 30-d survival in mice after exposure to a potentially lethal dose of 8 Gy.These results collectively indicate that PWA of Gui-Pi-Wan extracts is an effective radioprotective agent.