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患者女,69岁,高血压病病史10年,既往无糖尿病病史,于2003年4月开始口服吲达帕胺,服药前血糖4.2mmol/L。2012年12月体检测FPG 8.5mmol/L,后连续两日复查FPG分别为7.2、7.9mmol/L,诊断为糖尿病。未行饮食及降糖药物治疗,停服吲达帕胺1周后复查2次FPG分别为5.4、5.3mmol/L,1个月后复查FPG为4.9mmol/L。长期口服吲达帕胺可诱发糖尿病,且吲达帕胺对患者的糖代谢损害是可逆的。
Female patient, 69 years old, history of hypertension 10 years, no previous history of diabetes mellitus, beginning in April 2003 oral indapamide, blood glucose 4.2mmol / L before taking the drug. December 2012 body test FPG 8.5mmol / L, after a two-day review FPG were 7.2,7.9mmol / L, the diagnosis of diabetes. No diet and hypoglycemic drugs treatment, stopping taking indapamide 1 week after the second review FPG were 5.4,5.3 mmol / L, one month after the review FPG was 4.9mmol / L. Long-term oral indapamide can induce diabetes, and indomethacin on patients with glucose metabolism is reversible.