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目的 探讨功能磁共振成像在脑梗死超急性期的诊断价值。方法 采用GESigna 1.5T超导MR系统 ,对 2 9例被高度怀疑急性脑梗死且发病 6h以内的病人分别行弥散加权成像 (DWI) ,灌注成像 (PWI) ,氢质子磁共振波谱分析 (1H MRS)及常规MRIT1 W ,T2 W ,PD W检查。经工作站Functool软件包分析处理获得量值。结果 4例在临床和影像学随访后排除了脑梗死。 2 5例超急性脑梗死的fMRI检查结果为 :DWI ,PWI和常规MRI的敏感性分别为 10 0 % ,88%和 8% ;特异性均为 10 0 %。 3例经1H MRS检查结果为N 乙酰天门冬氨酸 (NAA)下降 ,含碱代谢物 (Cho)和肌酸 /磷酸肌酸 (Cr)无明显变化 ,出现乳酸 (Lac)峰 ,符合超急性期脑梗死的代谢特征。结论 功能磁共振成像在超急性脑梗死诊断方面优于常规MRI,对脑梗死的治疗有指导意义
Objective To investigate the diagnostic value of functional magnetic resonance imaging in patients with hyperacute cerebral infarction. Methods Twenty-nine patients with highly suspected acute cerebral infarction within 6 hours after onset of disease were treated with diffusion weighted imaging (DWI), perfusion imaging (PWI) and 1H MRS (1H MRS) with GESigna 1.5T superconducting MR system. ) And conventional MRIT1 W, T2 W, PD W examination. Through the workstation Functool package analysis and processing to obtain the value. Results Four patients were excluded from cerebral infarction after clinical and imaging follow-up. The fMRI results of 25 cases of hyperacute cerebral infarction were: the sensitivity of DWI, PWI and routine MRI were 100%, 88% and 8% respectively; the specificity was 100%. The results of 1H MRS showed that N-acetyl-aspartate (NAA) decreased, while the contents of Cho and creatine / creatine (Cr) did not change significantly, and lactic acid (Lac) Metabolic characteristics of cerebral infarction. Conclusion FMRI is superior to conventional MRI in the diagnosis of hyperacute cerebral infarction, which is instructive for the treatment of cerebral infarction