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目的 筛选单纯疱疹病毒 I型蛋白组中的 PACS- 1结合蛋白 .方法 根据筛选标准 ,利用 Scan Prosite和 PSORT软件对蛋白质进行分析 ,并结合相关文献中的实验数据对分析结果进行校正 .结果 该方法可有效地筛选出 PACS- 1结合蛋白 .利用该方法 ,在单纯疱疹病毒 I型蛋白组中 ,共筛选出可能与 PACS- 1结合的蛋白质 33种 .结论 建立了一种有效的筛选 PACS- 1结合蛋白的方法 .筛选出的单纯疱疹病毒 I型的 PACS- 1结合蛋白 ,将为研究 PACS- 1在疱疹病毒发生及潜伏性感染中的作用提供指导 .
Objective To screen the PACS-1 binding protein in herpes simplex virus type I proteome.Methods According to the screening criteria, the proteins were analyzed by Scan Prosite and PSORT software, and the experimental data in the related literatures were used to correct the analysis results.Results The method PACS-1 binding protein could be effectively screened.This method was used to screen out 33 proteins that may bind to PACS-1 in the herpes simplex type I proteome.Conclusion An effective screening method for PACS-1 Binding protein method.Screening of the herpes simplex virus type I PACS-1 binding protein, will provide guidance for the study of PACS-1 in the herpes virus and latent infection.