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本文试图验证利用转基因植物表达麻疹抗原开发口服亚单位麻疹疫苗策略的可行性。 为了在烟草中表达麻疹病毒 ( MV)血凝素 ( H)蛋白 ,作者将 1 .8kb包含 H蛋白编码区的基因片段克隆入植物表达载体 p RTL2 ,构建了三种不同的表达载体 :p RTL 2 - H(只有 H基因 ) ;p RTL2 - H/
This article attempts to validate the feasibility of developing an oral subunit measles vaccine using transgenic plants to express measles antigens. In order to express the hemagglutinin (H) protein of measles virus (MV) in tobacco, the authors cloned a 1.8 kb gene fragment containing the H protein coding region into the plant expression vector p RTL2 to construct three different expression vectors: p RTL 2 - H (H gene only); p RTL2 - H /