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目的探讨原发性机网膜色素变性（RP）患者血清中微量元素锌（Zn）、铜（Cu）、铁（Fe）、钙（Ca）、镁（Mg）的含量与RP发病的关系。方法应用PE5000型原子吸收分光光度计测定26例RP患者血清中Zn、Cu、Fe、Ca、Mg的含量。结果RP患者血清Zn、Cu值较生理值明显降低，差异有极显著性。血清Fe、Ca含量较生理值升高，差异有极显著性。Mg的含量与生理值无明显差异。结论RP的发病可能与Zn、Cu、Fe、Ca尤期是Zn、Cu的代谢异常有关。
Objective To investigate the relationship between serum levels of trace elements (Zn), copper (Cu), iron (Fe), calcium (Ca) and magnesium (Mg) in patients with primary retinal pigment epithelium (RP) Methods The contents of Zn, Cu, Fe, Ca and Mg in 26 RP patients were determined by PE5000 atomic absorption spectrophotometer. Results Serum levels of Zn and Cu in RP patients were significantly lower than those in physiological values, with significant differences. Serum Fe, Ca content than the physiological value increased, the difference was significant. Mg content and physiological values no significant difference. Conclusion The incidence of RP may be related to the abnormal metabolism of Zn and Cu in Zn, Cu, Fe and Ca, especially in Zn and Cu.